I think my answer depends on how strong the fame nuke is. In the regime of weak effect, I would basically use it as a way to experiment on the culture at large. In stronger regimes, I have to choose it so that the effect is something beneficial for the wider culture. (even if I would like it to be an experiment, to be something that escapes my predictions) In very strong regimes where it turns every other person into something of an internet-type celebrity, I basically have to drop it in the least dysfunctional, most persistently impoverished, whitest area I can find.
So I have been considering the lower effect regime, where I have the most interesting criteria. I’m imagining something where there are maybe a few dozen semi-celebrities in a selected small town, or a larger number at lower proportion in a regular town or larger city. The town gets a bit of tourism as a result, depending on how accessible it is. People might expect you to know about the town as if it is a capital city or a unique local curiosity.
The fame nuke does not obviate language barriers. If I fame-nuked somewhere in Quebec, fans from the USA wouldn’t understand French unless they took classes for it. Which they might, it is FSI category I not FSI category IV like Korean, Japanese or Chinese. (24-30 weeks vs 88 weeks)
Quebec might be a good subject actually, but I don’t know anywhere special in Quebec. Just Quebec city, the biggest whitest one?
New Hampshire - free state project community. Libertarians who move across states are very interesting people, very entrepreneurial. Not world shaking geniuses, but they like to live life. That could be healthy for the culture, and interesting. The culture of intentional communities in general would be a cool thing to broadcast, if you could somehow fame-nuke some of the less cultish ones.
The motivating candidate for this thought experiment is Louisville Kentucky, focused on their the sizeable Cuban community. I suspect there are two types of false partisan around there. (I have no experience in the area, this is all speculation based on stereotypes that might not apply specifically to the citizens in general or the Cubans.)
Kentucky people are covert rightists in denial. They come from a union-democrat tradition in contrast with their true rightist feelings, for a long time people would register as Democrats as a sort of tradition. For a while there was a tendency to vote Republican for the presidency, and vote nominally democrat for the state and local. (This might be more interesting if I could travel back in time a few decades and then fame-nuke them, but their old folks are still alive and kicking so they still set some odd context)
Cubans, like a mirror image, have a legacy reason why they want to be right wing. Their history of leaving Cuba and making it in the USA positions them as traditionally anti-communist and hence anti-leftist. But, at their heart they are more libertine and progressive than the typical American. If the Cubans in Louisville are like this, that could be a fascinating contrast to push into the culture for a decade. If there was more contemplation of the weird interactions between partisan identity and actual ethics that would be cool and probably beneficial.
The largest city I’ve considered is the District of Columbia for how notoriously disagreeable they are, but I can’t in good conscience do that given their demographics. (black, female)